An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract
نویسندگان
چکیده
منابع مشابه
An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract
BACKGROUND The MCE, Momordica charantia fruit extract Linn. (Cucurbitaceae) have been documented to elicit hypoglycemic activity on various occasions. However, due to lack of standardization of these extracts, their efficacy remains questionable. The present study was undertaken by selecting a well standardised MCE. This study reports hypoglycemic and antilipidemic activities of MCE employing r...
متن کاملEvidence of Immunosuppressive and Th2 Immune Polarizing Effects of Antidiabetic Momordica charantia Fruit Juice
The mechanism of action of the antidiabetic capacity of Momordica charantia is still under investigation. Here, we assessed phytochemical compositions, antioxidant activity, and effects of total and filtered fruit and leafy stem juices of Momordica charantia on human T cell proliferation and differentiation through quantification of Th1/Th2 cytokines. In the absence of stimulation, total fruit ...
متن کاملCharacterization of phytoconstituents and evaluation of antimicrobial activity of silver-extract nanoparticles synthesized from Momordica charantia fruit extract
BACKGROUND Our present study was conducted to characterize the phytoconstituents present in the aqueous extract of Momordica charantia and evaluate the antimicrobial efficacy of silver-extract nanoparticles (Ag-Extract-NPs). METHODS Silver nanoparticles (AgNPs) were prepared by reducing AgNO3; and NaBH4 served as reducing agent. After screening of phytochemicals; AgNPs and aqueous extract wer...
متن کاملSeasonal Variation in the Anti-Diabetic and Hypolipidemic Effects of Momordica charantia Fruit Extract in Rats
Aims: To investigate seasonal variation in anti-diabetic and hypolipidemic activities of Momordica charantia fruits harvested at different seasons of the year, namely spring, summer, autumn and winter. Methodology: Air-dried and pulverized fruit samples were extracted by soaking in 70% methanol for 72h. The filtrate was concentrated using rotary evaporator. The yields of spring (MME), summer (J...
متن کاملAntiglycation and Antioxidant Properties of Momordica charantia
The accumulation of advanced glycation endproducts (AGEs) and oxidative stress underlie the pathogenesis of diabetic complications. In many developing countries, diabetes treatment is unaffordable, and plants such as bitter gourd (or bitter melon; Momordica charantia) are used as traditional remedies because they exhibit hypoglycaemic properties. This study compared the antiglycation and antiox...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2007
ISSN: 1472-6882
DOI: 10.1186/1472-6882-7-29